| Barcelona outclassed by Zaragoza
ZARAGOZA, Spain -- Barcelona were outclassed by Real Zaragoza as they went down 1-0 at La Romareda on Saturday and the defeat offered their title rivals renewed hope of depriving the Catalans of a third successive league title. Diego Milito took the credit for the goal but it was unclear whether he actually got a touch to the ball after fellow Argentine Andres D'Alessandro had threaded an acute-angled shot into the net from the byline 13 minutes into the second half. The scoreline did little to reflect the domination of a Zaragoza side that had Barcelona on the ropes for most of the game. Barca coach Frank Rijkaard's decision to opt for a three-man defense played into Zaragoza's hands from the start and his side were fortunate not to concede several more goals.
GSK Initiates First Global Phase III Study of TYKERB(R) (Lapatinib) in Head and Neck Cancer
BARCELONA, Spain, Feb. 26 /PRNewswire/ -- GlaxoSmithKline (GSK) today announced the start of an international Phase III trial of its investigational cancer treatment TYKERB(R) (lapatinib) in squamous cell carcinoma of the head and neck (SCCHN). This announcement coincided with the International Meeting on Innovative Approaches in Head & Neck Oncology, Barcelona, Spain, February 22-24 supported by the European Society for Therapeutic Radiology and Oncology (ESTRO), where GSK presented results from a Phase I study of lapatinib in SCCHN. Lapatinib is an investigational drug that is not yet approved for marketing by any regulatory body. This large adjuvant trial will compare the effectiveness of oral lapatinib versus placebo given in high-risk patients following surgery. SCCHN is the sixth most common cancer worldwide (1): 600,000 people are diagnosed with SCCHN annually (1), 40,000 in the United States (2) and 100,800 in Europe alone.(3) 40,000 people die from the disease every year.(3) The design of this Phase III trial was based on recent results from two large-scale, independent randomized studies which have established the addition of chemotherapy to radiation therapy as the new standard of care in the post-operative treatment of high-risk SCCHN patients with additional use of chemotherapy.(4, 5) However, research suggests that approximately one quarter to one third of advanced head and neck cancers that are primarily treated with surgery and radiation therapy come back following treatment.(4, 5) "The initiation of this trial represents another exciting step towards understanding the role of lapatinib in other tumor types beyond breast cancer," says Professor Jean Bourhis, Head of Radiation-Oncology Department, Institute Gustave Roussy, France and principal investigator for this trial.
Outclassed Barca slip to 1-0 defeat at Zaragoza
MADRID (Reuters) - Barcelona were outclassed by Real Zaragoza as they went down 1-0 at La Romareda on Saturday in a defeat which will give their title rivals renewed hope of depriving the Catalans of a third successive league title. Diego Milito took the credit for the goal but it was unclear whether he actually got a touch to the ball after fellow Argentine Andres D'Alessandro had threaded an acute-angled shot into the net from the byeline 13 minutes into the second half. The scoreline did little to reflect the domination of a Zaragoza side that had Barcelona on the ropes for most of the game. Barca coach Frank Rijkaard's decision to opt for a three-man defence played into Zaragoza's hands from the start and his side were fortunate not to concede several more goals.
Man United unhappy over Ronaldo pursuit
Manchester United director Sir Bobby Charlton admits the club are becoming 'cheesed off' by Real Madrid and Barcelona continuing their pursuit of Portuguese star Cristiano Ronaldo. The Spanish giants have both been strongly linked with the 22-year-old winger despite statements from the club that he is going nowhere. He has scored 18 goals so far this season to keep United on course for a repeat of their 1999 treble. Charlton believes the player should be left alone to focus on playing for United and is becoming increasingly frustrated by other clubs refusing to back off. 'Anybody associated with Manchester United would be a little bit perturbed when a few months before the end of a very important season someone starts to make claims for him. I don't think it's correct,' Charlton said.
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